CardiOS 60 Capsules

CardiOS is a unique formulation which simultaneously targets cardiovascular, bone health and declining DHEA-Cortisol balance, all of which significantly deteriorate during the ageing process.

The formulated ingredients in CardiOS are designed to favourably contribute to reducing these combined elements of chronic disease.

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Product Details

CardiOS is beneficial for those approaching mid and later-life to support declining physiology, especially common to both Andropausal men and Menopausal & Post-Menopausal women.

CardiOS is indicated for:

  • Cardiovascular disease, incl. endothelial dysfunction with calcification of smooth muscle and arterial plaque
  • Osteoporotic and osteopenic bone loss
  • Cognitive impairment, affecting working memory and psychomotor performance
  • Anxiety, depression, insomnia and related conditions
  • Declining antioxidant/ detoxification enzyme activity and impairment in other endogenous defences

Serving Type: Vegetable Cellulose Size ’00’ Capsule (suitable for vegetarians).

Features

Clinical data shows that compounds in CardiOS may:

  • Facilitate integration of calcium into bone and to remove unwanted calcium from arteries
  • Assist in the synthesis of the bone-forming protein osteocalcin
  • Help reduce the morning cortisol levels which promote a degree of heightened anxiety
  • Assist in reducing inflammation as well as helping to restore the normal function to the lining of blood vessels.
  • Activate cellular defences
Ingredients

Each Size ‘00’ CardiOS VegeCap® contains:

  • 12.5 mcg Cholecalciferol (Vitamin D3); 500 IU
  • 90 mcg Menaquinone-7 (Vitamin K2); (MenaQ7®)
  • 100 mg 100% Whole Broccoli Sprout Powder Brassica oleracea var. italica (EnduraCell®)
  • 625 mg Withania somnifera dry root ext. (Sensoril®). (Contains withanolides of Withania somnifera; 30 mg).

NOTE: Cell-Logic EnduraCell® is hydroganically grown in a carefully controlled environment to maximise bioactivity. Our hydroganic growing process does not use any herbicides, pesticides or other harmful chemicals. CardiOS is GMO free.

Application

Recommended Daily Dosage:

Adults: Take 1 capsule twice daily or as directed by a Health Care Practitioner.

Children: Not recommended for children.

Application notes: Very occasionally, adverse effects have been reported after ingestion of either fresh broccoli sprouts or supplements manufactured from fresh sprouts. These effects are typically gastrointestinal in nature and may include nausea, bloating, gastro-abdominal discomfort, and diarrhoea. The skin as an organ of elimination may also be temporarily impacted, together with neural function which is sensitive to redox-inflammation imbalances. The limited data available seem to indicate that gastro-intestinal effects are generally limited to those with pre-existing conditions and in particular to those with dysbiosis associated with a perturbed gut ecosystem.

Dose Titration: In sensitive individuals experiencing any of the aforementioned concerns, titration up to a full dose from a low starting dose allows progressive correction of the underlying causes without overloading the patient’s ability to adapt. The goal is to enable the patient to tolerate the full sulforaphane dose at a pace that eliminates symptoms whilst simultaneously restoring homeostasis.

Instructions for Dose Titration:
1. Discontinue all source of SFN – cruciferous vegetables, broccoli sprout powder and/or capsules.

2. Assuming symptoms abate, resume SFN at a very small dose. This dose may be as little as will fit on the tip of a sharp vegetable knife blade. EnduraCell® powder is the best option, although capsules can be opened.

3. Take this dose daily for a few days to ensure that the gastrointestinal system feels comfortable.

4. Gradually increase the dose by taking a second similar dose each day.

5. Repeat the process by increasing a little each day, monitoring symptoms to determine daily dose.

6. Typically, within 2 weeks, the standard recommended dose will not produce significant ill effects. In severe cases, tolerance may take weeks more to achieve. Be guided by the patient’s response.

7. Those with known dysbiosis or other gastrointestinal issues will typically find that these symptoms have either partially or fully cleared. Cruciferous vegetables can be re-introduced at this stage.

8. Where a patient has been intolerant to other foods, their introduction can be trialled one at a time.

Warnings

Store below 30°C

Direct-acting antioxidants
When mega-doses of direct-acting antioxidants are consumed, the cell may become saturated, masking the pro-oxidant signals the cell needs to defend itself via Nrf2. Unless there is deficiency, vitamin C and any other direct-acting antioxidant supplements like A, E, beta-carotene & NAC, will inhibit the cell’s ability to upregulate its own antioxidant, detoxification
and other cytoprotective genes. If needed at all, antioxidant supplements should be reduced to quantities no greater than RDI levels found in a plant rich diet.

Cancer and treatments
Chemotherapy and Radiation: Because cancer cells ‘hijack’ the cell’s defence mechanisms, it is unknown whether SFN, GliSODin or other protective plant molecules in normal cells might also increase a cancer cell’s ability to protect itself. It is therefore advisable to avoid prescribing SFN, GliSODin and other concentrated plant extracts in those diagnosed with cancer – or undergoing treatments such as chemotherapy and radiation.

Anti-coagulant medications
The RDI for Vitamin K1 is 700 mcg. A mature broccoli vegetable contains 85 mcg of Vit K1. The Vitamin K1 content of broccoli sprouts is low in comparison, with one 700 mg capsule of EnduraCell® BioActive containing approximately 7 mcg of Vitamin K1. While Vitamin K2 appears not to interfere with coagulation, it is recommended that the patient’s clinician be consulted to prescription of GFC.

Goitrogens and thyroid function
Broccoli sprouts do not contain any significant goitrogens as found in the mature broccoli vegetable, so there are no contraindications to prescribing Cell-Logic’s broccoli sprout formulae in thyroid conditions.

Evidence

Bolland MJ et al. Calcium intake and risk of fracture: systematic review BMJ 2015;351:h4580

McCann JC, Ames BN. Vitamin K, an example of triage theory: is micronutrient inadequacy linked to diseases of ageing? Am J Clin Nutr. 2009;90:889-907

Knapen MH et al. Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women. Osteoporosis. Int. 2013 Sep;24(9):2499-507.

Knapen MH et al. Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial. Thromb Haemost. 2015 May;113(5):1135-44.

Auddy B et al. A Standardized Withania Somnifera Extract Significantly Reduced Stress-Related Parameters in Chronically-Stressed Humans: A Double-Blind, Randomized, Placebo-Controlled Study. JANA Vol. 11(1):2008.50-56