From the Scientific Literature

Sulforaphane treatment of autism spectrum disorder (ASD)

Kanwaljit Singh, Susan L. Connors, Eric A. Macklin et al. Proceedings of the National Academy of Sciences. 2014;111(43):15550

Abstract: Autism spectrum disorder (ASD), encompassing impaired communication and social interaction, and repetitive stereotypic behavior and language, affects 1–2% of predominantly male individuals and is an enormous medical and economic problem for which there is no documented, mechanism-based treatment. In a placebo-controlled, randomized, double-blind clinical trial, daily oral administration for 18 wk of the phytochemical sulforaphane (derived from broccoli sprouts) to 29 young men with ASD substantially (and reversibly) improved behavior compared with 15 placebo recipients.

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