EnduraDERM Cosmeceutical 30 Single 10g Sachets

Cell-Logic’s research innovators are acknowledged leaders in the field of Nutrigenomics, the science that governs the ability of food molecules to beneficially activate the expression of health-promoting genes.  With a unique base of natural plant ingredients, EnduraDERM has been developed using three powerful nutrigenomic compounds, Immunobiotic HKL-137, GliSODin® and Collagen Peptides, each shown in clinical trials to directly benefit skin, nails and hair by activating the expression of genes associated with:

1. Optimising immune defences
2. The ability of the skin to retain moisture
3. Upregulating the primary Antioxidant Enzymes, SOD, GPx and Catalase
4. Reducing skin wrinkling by increasing synthesis of pro-collagen and elastin
5. Increasing nail growth and reducing brittleness

EnduraDERM is a unique evidence-based nutrigenomic formulation with 3 Key Bioactives supported by 3 natural plant ingredients –

KEY BIOACTIVE INGREDIENT #1 Immunobiotic HKL-137

HKL-137 is derived from a new class of beneficial probiotic organism discovered by Japanese researchers to act as a potent immunobiotic.
More recently, another of its remarkable properties was discovered – its ability to retain moisture in the skin via a cellular molecule called hyaluronic acid (HA).
Ageing, stress, poor lifestyle habits and exposure to the elements can reduce the skin’s ability to synthesise HA, thereby allowing rapid skin dehydration and accelerated ageing.
HA is largely responsible for maintaining the moisture content of the keratinocyte and fibroblast skin cells, a function that helps the skin cells to retain moisture and plumpness.
Other HKL-137 studies reveal its significant benefit to the immune system overall.

KEY BIOACTIVE INGREDIENT #2 GliSODin®

Patented GliSODin® has been shown clinically as a potent inducer of these 3 major enzymes, protecting skin cells from sun damage and the signs of ageing.  GliSODin® has also been proven clinically to target dark spots as well as uneven skin tone, helping to brighten the complexion and unify its skin tone.

KEY BIOACTIVE INGREDIENT #3 Collagen Peptides

Collagen is a unique protein that provides the main building block of human skin and other tissues. Collagen plays a huge part in giving young complexions their much-admired plumpness and youthful bloom.  As we age, our ability to produce collagen declines but brilliant German scientists have developed specific collagen peptides that have been proven to slow the process. These peptides do this by sending ‘wake up’ signals to certain genes in our skin cells.
EnduraDERM includes these very same collagen peptides (Verisol®) that have been proven in clinical trials to reduce wrinkling and dehydration, at the same time enhancing nail growth and reducing brittleness.

EnduraDERM’S clinically proven cosmeceutical formulation is strengthened with the addition of three natural food-derived ingredients beneficial to general health and especially the health of skin, hair and nails.

• Camu Camu – is an Amazonian berry, naturally rich in Vitamin C and other beneficial plant molecules
• Bamboo Fibre – helps to nourish the ‘friendly’ Bifidobacteria that are beneficial for optimal digestive function
• Carrot Juice Concentrate –  is naturally rich in beta-carotene and other protective nutrients

EnduraDERM – All Natural Cosmeceutical Formulation

A cosmeceutical is an oral formulation containing natural bioactive food ingredients that nourish and enhance the complexion – from the INSIDE out! Each of the 3 key cosmeceutical ingredients has been proven in human clinical trials to benefit the complexion, hair and nails by activating skin-protective genes.

How to use EnduraDERM daily:

Simply mix one 10-gram sachet of EnduraDERM in ½ glass of filtered water, juice or other cooled or room temperature beverage of your choice. (Do not add to hot beverages which will destroy the natural enzymes essential to the product).

EnduraDERM contains no added sweeteners of any kind, enabling you to sweeten if required.  EnduraDERM is free from dairy, egg, soy, nuts, legumes, corn, yeast, added sugar or other sweeteners and has no artificial additives.

EnduraDERM is not recommended for those with coeliac disease as its GliSODin®  ingredient contains very small amounts of gliadin as part of its ability to activate the antioxidant enzymes SOD, GPx and Cat, and of the anti-inflammatory cytokine, IL-10. Those avoiding wheat due to suspected wheat intolerance do not typically react to GliSODin®.

1. Nakai H. et al. Lactobacillus plantarum L-137 upregulates hyaluronic acid production in epidermal cells and fibroblasts in mice. Microbiol Immunol. 2019 Sep;63(9):367-378.

2. Hirose Y. et al. Daily intake of heat-killed Lactobacillus plantarum L-137 augments acquired immunity in healthy adults J Nutr. 2006 Dec;136(12):3069-73.

3. Yoshitake R, et al. Beneficial Effect of Heat-Killed Lactiplantibacillus plantarum L-137 on Skin Functions in Healthy Participants: A Randomized, Placebo-Controlled, Double-Blind Study. Front Med (Lausanne). 2022 Jul 6;9:912280.

4. Pomarede N et al. Enhancing the Skin’s Natural Antioxidant Enzyme System by the Supplementation or Upregulation of Superoxide Dismutase, Catalase, and Glutathione Peroxidase. Tabor A, Blair RM, editors. Chapter 13 – Nutritional Cosmetics. Boston: William Andrew Publishing; 2009. p. 245-65.

5. Proksch E et al. Oral intake of specific bioactive collagen peptides reduces skin wrinkles and increases dermal matrix synthesis. Skin Pharmacol Physiol. 2014;27(3):113-9.

6. Hexsel D et al. Oral supplementation with specific bioactive collagen peptides improves nail growth and reduces symptoms of brittle nails. J Cosmet Dermatol. 2017 Dec;16(4):520-526.